![]() Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor immediately if any of the following side effects occur while taking dabigatran: More common Serious side effects of PradaxaĪlong with its needed effects, dabigatran (the active ingredient contained in Pradaxa) may cause some unwanted effects. Consider the risks and benefits before neuraxial intervention in patients anticoagulated or to be anticoagulated. If neurological compromise is noted, urgent treatment is necessary. Monitor patients frequently for signs and symptoms of neurological impairment. Factors that can increase the risk of developing epidural or spinal hematomas in these patients include: use of indwelling epidural catheters concomitant use of other drugs that affect hemostasis, such as NSAIDs, platelet inhibitors, other anticoagulants a history of traumatic or repeated epidural or spinal punctures a history of spinal deformity or spinal surgery optimal timing between administration of dabigatran etexilate and neuraxial procedures is not known. Consider these risks when scheduling patients for spinal procedures. These hematomas may result in long-term or permanent paralysis. If anticoagulation with dabigatran etexilate is discontinued for a reason other than pathological bleeding or completion of a course of therapy, consider coverage with another anticoagulant.Spinal/Epidural HematomaEpidural or spinal hematomas may occur in patients treated with dabigatran etexilate who are receiving neuraxial anesthesia or undergoing spinal puncture. Premature Discontinuation Increases The Risk Of Thrombotic EventsPremature discontinuation of any oral anticoagulant, including dabigatran etexilate, increases the risk of thrombotic events.
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